Silicosis in the Medical Journals This Month




Article: The Role of Pro- and Anti-Inflammatory Responses in Silica-Induced Lung Fibrosis Journal: Respiratory Research 2005 Oct 7;6(1):112 Authors: V. Barbarin, A. Nihoul, P. Mission, M. Arras, M. Delos, I. Leclercq, D. Lison, F. Huaux Summary: Based on recent challenges to what the authors say is the generally well-accepted opinion that chronic inflammation is a necessary component of lung fibrosis, the study aimed to compare lung response to fibrogenic silica particles in murine subjects using biochemical, histological, immunohistochemistry and cellular analyses. The results showed that rats treated with silica particles developed chronic and …





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