Journal Watch, Arthritis Drugs, September 2006

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Celecoxib for the Prevention of Sporadic Colorectal Adenomas

Journal: New England Journal of Medicine 2006 Aug 31;355(9):873-84

Authors: Bertagnolli M.M., Eagle C.J., Zauber A.G., Redston M., Solomon S.D., Kim K., Tang J., Rosenstein R.B., Wittes J., Corle D., Hess T.M., Woloj G.M., Boisserie F., Anderson W.F., Viner J.L., Bagheri D., Burn J., Chung D.C., Dewar T., Foley T.R., Hoffman N., Macrae F., Pruitt R.E., Saltzman J.R., Salzberg B., Sylwestrowicz T., Gordon G.B., Hawk E.T.

Summary: Studies showing that drugs that inhibit COX-2 reduce the number of colorectal adenomas in animals and patients with familial adenomatous polyposis …