Arthritis Drugs in the Medical Literature This Month - July 2006

Journal: Drug Safety: An International Journal of Medical Toxicology and Drug Experience 2006;29(7):621-32

Authors: S.P. Motsko, K.L. Rascati, A.J. Busti, J.P. Wilson, J.C. Barner, K.A. Lawson, J. Worchel

Summary: The search for NSAIDs with less gastrointestinal toxicity led to the introduction of the selective COX-2 inhibitors. However, following their introduction into the market, concerns have developed regarding their safety, particularly their cardiovascular safety. The purpose of this study was to assess the cardiovascular risk associated with long-term (>180 days …