Arthritis Drugs in the Medical Literature This Month - March 2006

Journal: Anesthesiology 2006 Mar;104(3):518-526

Authors: N.A. Nussmeier, A.A. Whelton, M.T. Brown, G.P. Joshi, R.M. Langford, N.K. Singla, M.E. Boye, K.M. Verburg

Summary: A randomized trial in which more than 1,000 patients received either parenteral parecoxib for 3 days and oral valdecoxib (Bextra) for the remainder of the treatment period, or placebo medications throughout. The aim of the study was to examine safety and analgesic efficacy of Bextra and its pro-drug in patients recovering from major, non-cardiac surgeries. According to …