Arthritis Drugs in the Medical Literature This Month - August 2006
August 18, 2006
| Quantitative Assessment of the Gastrointestinal and Cardiovascular Risk-Benefit of Celecoxib Compared to Individual NSAIDs at the Population Level |
Journal: Pharmacoepidemiology and Drug Safety 2006 Aug 9; [Epub ahead of print]
Authors: C. Varas-Lorenzo, A. Maguire, J. Castellsague, S. Perez-Gutthann
Summary: Our objective was to estimate the net cardiovascular (CV) (coronary heart disease, stroke, congestive heart failure) and gastrointestinal (GI) (peptic ulcer complications) risk-benefit public health impact of the use of celecoxib compared to non-selective NSAIDs in the arthritis population. We simulated the natural history of CV and GI disease in the U.S. …
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