Arthritis Drugs in the Medical Literature This Month - January 2006
January 6, 2006
Low Dose Rofecoxib, Inflammation and Prostacyclin Synthesis in Acute Coronary Syndromes |
Journal: Roczniki Akademii Medycznej w Bialymstoku 2005;50:339-42
Authors: A.M. Kuklinska, W.J. Musial, K.A. Kaminski, P. Kralisz, W. Modrzejewski, B. Sobkowicz, S. Dobrzycki, S. Stec, I. Wojtkowska
Summary: This study was designed to assess the influence of low dose Vioxx on inflammatory mediators and prostacyclin synthesis in patients with acute coronary syndrome. In all, 29 patients were randomized to simvastatin alone or together with Vioxx and assessed after 30 days. The results indicated that low-dose COX-2 therapy exerts significant anti-inflammatory effects and …
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