Arthritis Drugs In the Medical Literature This Month





A Comparison of Reported Gastrointestinal and Thromboembolic Events Between Rofecoxib and Celecoxib Using Observational Data

Journal: Drug Safety 2005;28(9):803-16 Authors: R. Kasliwal, D. Layton, S. Harris, L. Wilton, S.A. Shakir Summary: A study comparing the incidence of gastrointestinal events and thromboembolic events reported for 15,286 and 17,458 patients prescribed Vioxx or Celebrex, respectively. Incidence rates of the first event during treatment within each thromboembolic and gastrointestinal group were calculated during the 270 days after the patient started receiving either drug. The results indicated that for the GI event groups, the adjusted relative …






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