Arthritis Drugs In the Medical Literature This Month

Tolerability and Adverse Events in Clinical Trials of Celecoxib in Osteoarthritis and Rheumatoid Arthritis: Systematic Review and Meta-Analysis of Information from Company Clinical Trial Reports

Journal: Arthritis Research & Therapy 2005;7(3):R644-45. Epub

Authors: R.A. Moore, S. Derry, G.T. Makinson, H.J. McQuay

Summary: The researchers extracted date from company clinical trial reports of randomized trials of Celebrex in arthritis patients in an effort to improve understanding of adverse events associated with the drug. A total of 31 trials involving nearly 40,000 patients and lasting 12 weeks or more were analyzed. Many of the trials compared Celebrex to other COX-2s …