Journal Watch, Arthritis Drugs, October 2006
October 1, 2006
1 Nonsteroidal Antiinflammatory Drugs and Acute Myocardial Infarction in Patients with No Major Risk Factors
Journal: Pharmacotherapy 2006 Oct; 26(10):1379-87
Authors: Jick H, Kaye JA, Russmann S, Jick SS
Summary: The study objective was to assess the risk of long-term use of five nonsteroidal antiinflammatory drugs (NSAIDs)-rofecoxib, celecoxib, ibuprofen, naproxen, and diclofenac-in relation to acute myocardial infarction. The design included five separate nested case-control studies, one for each NSAID, designed to minimize important biases present in other observational studies. We identified people aged 30-79 years who had a first recorded prescription for rofecoxib, celecoxib, ibuprofen, naproxen, …
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HarrisMartin’s Artificial Stone Silicosis Epidemic Litigation Conference
