Abstracts From the Literature

Drug: Celebrex/Vioxx Article: A Retrospective Review of the Effect of COX-2 Inhibitors on Blood Pressure Change Journal: American Journal of Therapeutics, 2003 Sep-Oct; 10(5): 311-17 Authors: J. Cho, C.E. Cooke, W. Proveaux

Summary: The researchers compared the difference between celecoxib (Celebrex) and rofecoxib (Vioxx) on blood pressure change by reviewing selected patients' medical records in the 90-day period before and after starting treatment with the arthritis drugs. The study consisted of 109 patients (52 Celebrex, 57 Vioxx) whose systolic blood pressure at baseline was comparable. After treatment began, the patients' records in the celecoxib group noted a non-significant decrease …