Arthritis Drugs In the Medical Literature This Month





Selective COX-2 Inhibitors and Risk of Myocardial Infarction

Publication: Journal of Vascular Research 2005 Jun 20;42(4):312-324 Authors: F. Krotz, T.M. Schiele, V. Klauss, H.Y. Sohn Summary: A review outlining the rationale for the development of selective COX-2 inhibitors and the pathophysiological consequences of selective inhibition of CoX-2 with a special focus on vasoactive prostaglandins. The article also describes coxibs currently on the market, evaluates the current knowledge of the risk of atherothrombotic events associated with taking the drugs and critically discusses the consequences drawn from these insights. Web site: http://www.karger.com/jvr

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