Journal Top Ten -- COLUMNS-Drugs & Supplements -- November 2006

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Seroquel

ARTICLE: 'The Safety of Quetiapine: Results of a Post-Marketing Surveillance Study on 1,728 Patients in England'

JOURNAL: Journal of Psychopharmacology. 2006 Nov 8; [Epub ahead of print]

SUMMARY: The safety of quetiapine as used in general practice in England was examined by prescription-event monitoring. Clinically useful information on 1,728 patients (median age 39 years; 53% female) were received. The most frequently reported event during the first month of treatment was 'drowsiness/ sedation' (47; 3% cohort). This was also the most frequently reported specified adverse drug reaction (ADR) to quetiapine (7; 11% of 65 reported ADRs) …