Journal Top Ten, COLUMNS-Mold, July 2005

ARTICLE: "Changing face of health-care associated fungal infections"

SUMMARY: The purpose of this review was to evaluate recent publications on the epidemiology, diagnosis and management of invasive fungal infections. Epidemiological surveys have highlighted significant differences between Europe and the United States regarding the incidence and etiology of Candida bloodstream infections. Today, invasive aspergillosis is occurring in a much broader patient population than the classical immunocompromised hosts and includes mechanically ventilated intensive care unit patients and patients receiving corticosteroids for treatment of chronic lung diseases. Diagnosis is often delayed in these patients …