Journal Top Ten, Columns-Asbestos, August 2005

TITLE: "Serum PDGF-AB in Pleural Mesothelioma"

JOURNAL: Tumour Biology. 2005 Aug 9;26(5):221-226 [Epub ahead of print]

AUTHORS: Filiberti R, Marroni P, Neri M, Ardizzoni A, Betta PG, Cafferata MA, Canessa PA, Puntoni R,Ivaldi GP, Paganuzzi M.

SUMMARY: Overexpression of platelet-derived growth factor (PDGF) has been observed in lung and pleural tumors. The aim of this study was to evaluate the diagnostic and prognostic role of serum PDGF in pleural mesothelioma (PM). Four groups of subjects were studied: 93 malignant PM patients, 33 primary non small cell lung cancer patients, 51 …