Journal Top Ten -- COLUMNS-Asbestos --December 2007

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TITLE: "Fluoro-edenite fibres induce lung cell apoptosis: an in vivo study"

AUTHORS: Loreto C, Rapisarda V, Carnazza ML, Musumeci G, Valentino M, Fenga C, Martinez G.

JOURNAL: Histology and Histopathology. 2008 Mar;23(3):319-26.

SUMMARY: The authors of the study had previously shown that apoptosis in the lungs of sheep exposed to fluoro-edenite fibres is induced via the receptor pathway. The present study was performed to gain further insights into the mechanisms of activation of programmed cell death induced by the fibres. Fluoro-edenite fibres are similar in size and morphology to some amphibolic asbestos fibres. The results are …